RTN1 (Isoform RTN1-C) rabbit pAb
Ucallm_WP6576-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | RTN1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 85kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RTN1 (Isoform RTN1-C) |
| Specificity | This antibody detects endogenous levels of RTN1 (Isoform RTN1-C) at Human, Mouse,Rat |
| Gene Name | RTN1 NSP |
| Protein Name | Reticulon-1 (Neuroendocrine-specific protein) |
| Other Name | |
| Species | Human |
| Gene ID | 6252 |
| Uniprot | Q16799, |
| Species.1 | Mouse |
| Gene ID.1 | 104001 |
| Uniprot.1 | Q8K0T0, |
| Species.2 | Rat |
| Gene ID.2 | 116644 |
| Uniprot.2 | Q64548 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein . |
| Tissue Expression | Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation. |
| Signaling_pathway | |
| Research Areas | |
| Function | Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. |
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