Price range: $268.00 through $328.00
Background:
This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014],
| Target | Sideroflexin-4 |
| Reactivity | Human |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 37kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SFXN4. AA range:1-50 |
| Sequence | |
| Specificity | Sideroflexin-4 Polyclonal Antibody detects endogenous levels of Sideroflexin-4 protein. |
| Gene Name | SFXN4 |
| Protein Name | Sideroflexin-4 |
| Other Name | SFXN4; / BCRM1; / Sideroflexin-4; / Breast cancer resistance marker 1 |
| Species | Human |
| Gene ID-1 | 119559 |
| Uniprot | Q6P4A7, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | Q925N1 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014], |
| Cellular Localization | Mitochondrion inner membrane; Multi-pass membrane protein . |
| Tissue Expression | Mammary tumor,Placenta,Tongue, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Potential iron transporter.,similarity:Belongs to the sideroflexin family., |
| RRID |
