Product details
Background:
- Please choose product options by visiting SLC19A3 rabbit pAb.
SLC19A1 rabbit pAb
Ucallm_WP7001-50
Price range: $268.00 through $328.00
Specifications
| Target | SLC19A1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 65kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SLC19A1 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of SLC19A1 at Human, Mouse,Rat |
| Gene Name | SLC19A1 FLOT1 RFC1 |
| Protein Name | Folate transporter 1 (FOLT) (Intestinal folate carrier 1) (IFC-1) (Placental folate transporter) (Reduced folate carrier protein) (RFC) (Solute carrier family 19 member 1) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 6573 |
| Uniprot | P41440, |
| Species.1 | Mouse |
| Gene ID-2 | 20509 |
| Uniprot.1 | P41438, |
| Species.2 | Rat |
| Gene ID-3 | |
| Uniprot.2 | Q62866 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Apical cell membrane; Multi-pass membrane protein . Basolateral cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Placenta, liver, and to a much smaller extent, in lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Transporter that mediates the import of reduced folates and a subset of cyclic dinucleotides . Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate . Also able to mediate the import of antifolate drug methotrexate . Acts as an importer of immunoreactive cyclic dinucleotides, such as cyclic GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol, and its linkage isomer 3'-3'-cGAMP . Mechanistically, acts as an antiporter, which export of intracellular organic anions to facilitate uptake of its substrates . 5-amino-4-imidazolecarboxamide riboside (AICAR), when phosphorylated to AICAR monophosphate, can serve as an organic anion for antiporter activity . |
| RRID |
Please login to post questions
Related products
