Spectrin β V Polyclonal Antibody
Product details
Background:
similarity:Belongs to the spectrin family., similarity:Contains 1 PH domain., similarity:Contains 2 CH (calponin-homology) domains., similarity:Contains 31 spectrin repeats., subcellular location:Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells., subunit:Probably associates with an alpha chain., tissue specificity:Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.,
Specifications
| Size | 50μL/100μL |
| Target | Spectrin β V |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 417kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SPTBN5. AA range:481-530 |
| Specificity | Spectrin β V Polyclonal Antibody detects endogenous levels of Spectrin β V protein. |
| Gene Name | SPTBN5 |
| Protein Name | Spectrin beta chain non-erythrocytic 5 |
| Other Name | SPTBN5; / BSPECV; / HUBSPECV; / HUSPECV; / Spectrin beta chain; / non-erythrocytic 5; / Beta-V spectrin |
| Species | Human |
| Gene ID | 51332 |
| Uniprot | Q9NRC6 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton. Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells. |
| Tissue Expression | Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 2 CH (calponin-homology) domains.,similarity:Contains 31 spectrin repeats.,subcellular location:Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.,subunit:Probably associates with an alpha chain.,tissue specificity:Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart., |
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