Product details
Background:
SPY1 rabbit pAb
Ucallm_WP4269-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SPY1 |
| Reactivity | Human, Mouse |
| Applications | IF, WB, CoIP |
| MW(Calculated) | 35kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IP 1:50-100; IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SPY1 AA range: 129-179 |
| Specificity | This antibody detects endogenous levels of SPY1 at Human/Mouse |
| Gene Name | SPRY1 |
| Protein Name | SPY1 |
| Other Name | |
| Species | Human |
| Gene ID | 10252 |
| Uniprot | O43609, |
| Species.1 | Mouse |
| Gene ID.1 | 24063 |
| Uniprot.1 | Q9QXV9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein. Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor). |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.,Function:May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.,induction:By FGF signaling.,similarity:Belongs to the sprouty family.,similarity:Contains 1 SPR (sprouty) domain.,subcellular location:Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor)., |
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