Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SRP14 AA range: 25-75
Specificity
This antibody detects endogenous levels of SRP14 at Human/Mouse
Gene Name
SRP14
Protein Name
SRP14
Other Name
Species
Human
Gene ID
6727
Uniprot
P37108,
Species.1
Mouse
Gene ID.1
100504988
Uniprot.1
P16254
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm.
Tissue Expression
Signaling_pathway
Research Areas
>>Protein export
Function
Function:Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.,online information:Signal recognition particle entry,similarity:Belongs to the SRP14 family.,subunit:Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.,