Price range: $268.00 through $328.00
Background:
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
| Size | 50μL/100μL |
| Target | T3JAM |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 64kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human T3JAM. AA range:251-300 |
| Specificity | T3JAM Polyclonal Antibody detects endogenous levels of T3JAM protein. |
| Gene Name | TRAF3IP3 |
| Protein Name | TRAF3-interacting JNK-activating modulator |
| Other Name | TRAF3IP3; / T3JAM; / TRAF3-interacting JNK-activating modulator; / TRAF3-interacting protein 3 |
| Species | Human |
| Gene ID | 80342 |
| Uniprot | Q9Y228, |
| Species.1 | Mouse |
| Gene ID.1 | 215243 |
| Uniprot.1 | Q8C0G2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane . Golgi apparatus membrane; Single-pass type IV membrane protein . Lysosome membrane . Mitochondrion outer membrane . Accumulates on the mitochondria after virus infection. . |
| Tissue Expression | Blood,Lung adenocarcinoma, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May function as an adapter molecule that regulates TRAF3-mediated JNK activation.,subunit:Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain., |
