TBA8 Polyclonal Antibody
Ucallm_WP2207-50
Price range: $268.00 through $328.00
Product details
Background:
TUBA8 encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. TUBA8 (Tubulin Alpha 8) is a Protein Coding gene. Diseases associated with TUBA8 include Cortical Dysplasia, Complex, With Other Brain Malformations 8 and Optic Nerve Hypoplasia. Among its related pathways are Development Slit-Robo signaling and Cytoskeleton remodeling Neurofilaments.
Specifications
| Size | 50μL/100μL |
| Target | TBA8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TBA8 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TUBA8 TUBAL2 |
| Protein Name | Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) |
| Other Name | |
| Species | Human |
| Gene ID | 1962 |
| Uniprot | Q9NY65, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9JJZ2, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q6AY56 |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Tissue Expression | Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Peroxisome;Organismal Systems >> Endocrine system >> PPAR signaling pathway |
| Research Areas | >>Phagosome; / >>Apoptosis; / >>Tight junction; / >>Gap junction; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Huntington disease; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Pathogenic Escherichia coli infection; / >>Salmonella infection |
| Function | protein complex assembly, microtubule-based process, microtubule-based movement, cellular macromolecular complex subunit organization, cellular macromolecular complex assembly, cellular protein complex assembly, macromolecular complex subunit organization, protein polymerization, macromolecular complex assembly, protein complex biogenesis, |
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