Price range: $268.00 through $328.00
Background:
function:May be involved in cellular transformation., PTM:N-glycosylated., similarity:Belongs to the TDE1 family., tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,
| Size | 50μL/100μL |
| Target | TDE1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 52kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SERC3. AA range:361-410 |
| Specificity | TDE1 Polyclonal Antibody detects endogenous levels of TDE1 protein. |
| Gene Name | SERINC3 |
| Protein Name | Serine incorporator 3 |
| Other Name | SERINC3; / DIFF33; / TDE1; / SBBI99; / Serine incorporator 3; / Tumor differentially expressed protein 1 |
| Species | Human |
| Gene ID | 10955 |
| Uniprot | Q13530, |
| Species.1 | Mouse |
| Gene ID.1 | 26943 |
| Uniprot.1 | Q9QZI9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable). . |
| Tissue Expression | Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues. |
| Signaling_pathway | |
| Research Areas | >>Viral life cycle - HIV-1 |
| Function | Function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues., |
