THIOM Polyclonal Antibody
Ucallm_WP2494-50
Price range: $268.00 through $328.00
Product details
Background:
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | THIOM |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 18kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | THIOM Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TXN2 TRX2 |
| Protein Name | Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) |
| Other Name | |
| Species | Human |
| Gene ID | 25828 |
| Uniprot | Q99757, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P97493, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P97615 |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Widely expressed in adult (at protein level) and fetal tissues. |
| Signaling_pathway | Organismal Systems >> Immune system >> NOD-like receptor signaling pathway;Human Diseases >> Neurodegenerative disease >> Parkinson disease |
| Research Areas | >>NOD-like receptor signaling pathway; / >>Parkinson disease; / >>Salmonella infection; / >>Fluid shear stress and atherosclerosis |
| Function | Function:Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Monomer.,tissue specificity:Widely expressed in adult (at protein level) and fetal tissues., |
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