Price range: $268.00 through $328.00
Background:
The protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for TMPO.
| Size | 50μL/100μL |
| Target | TMPO |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 75kD,50kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic peptide from human protein at AA range: 1-50 |
| Specificity | The antibody detects endogenous TMPO protein |
| Gene Name | TMPO LAP2 |
| Protein Name | thymopoietin |
| Other Name | TMPO LAP2 |
| Species | Human |
| Gene ID | 7112 |
| Uniprot | P42166;P42167 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. Chromosome. Expressed diffusely throughout the nucleus. |
| Tissue Expression | Expressed in many tissues. Most abundant in adult thymus and fetal liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | regulation of transcription, |
