TOM70 rabbit pAb
Ucallm_WP5969-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TOMM70 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 67kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TOM70 |
| Specificity | This antibody detects endogenous levels of TOM70 at Human, Mouse,Rat |
| Gene Name | TOMM70A KIAA0719 TOM70 |
| Protein Name | Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) |
| Other Name | |
| Species | Human |
| Gene ID | 9868 |
| Uniprot | O94826, |
| Species.1 | Mouse |
| Gene ID.1 | 28185 |
| Uniprot.1 | Q9CZW5, |
| Species.2 | Rat |
| Gene ID.2 | 304017 |
| Uniprot.2 | Q75Q39 |
| Cellular Localization | Mitochondrion outer membrane; Single-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Mitophagy - animal |
| Research Areas | |
| Function | Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner . Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection . Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis . |
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