SKU: WP14854 Categories: ,

TRIM16 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14854-100
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Product details

Background:

This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetTRIM16
ReactivityHuman, Mouse
ApplicationsIHC, IF, ELISA
MW(Calculated)64kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human TRIM16. AA range:31-80
SpecificityTRIM16 Polyclonal Antibody detects endogenous levels of TRIM16 protein.
Gene NameTRIM16
Protein NameTripartite motif-containing protein 16
Other NameTRIM16; / EBBP; / Tripartite motif-containing protein 16; / Estrogen-responsive B box protein
SpeciesHuman
Gene ID10626
UniprotO95361,
Species.1Mouse
Gene ID.1
Uniprot.1Q99PP9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm .
Tissue ExpressionHighest levels found in testis, ovary, small intestine, colon, placenta, heart, skeletal muscle and mammary gland. More highly expressed in the fetus than in the corresponding adult tissues. Expressed in basal keratinocytes.
Signaling_pathway
Research Areas
FunctionFunction:May play a role in the regulation of keratinocyte differentiation.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 2 B box-type zinc fingers.,tissue specificity:Highest levels found in testis, ovary, small intestine, colon, placenta, heart, skeletal muscle and mammary gland. More highly expressed in the fetus than in the corresponding adult tissues. Expressed in basal keratinocytes.,
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