SKU: WP7600 Categories: ,

TRMT5 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7600-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTRMT5
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)56kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TRMT5
SpecificityThis antibody detects endogenous levels of TRMT5 at Human, Mouse
Gene NameTRMT5 KIAA1393 TRM5
Protein NametRNA (guanine(37)-N1)-methyltransferase (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog)
Other Name
SpeciesHuman
Gene ID57570
UniprotQ32P41,
Species.1Mouse
Gene ID.176357
Uniprot.1Q9D0C4
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion matrix . Nucleus . Cytoplasm . Predominantly in the mitochondria and in the nucleus. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionInvolved in mitochondrial tRNA methylation . Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
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