TRMT5 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TRMT5 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TRMT5 |
| Specificity | This antibody detects endogenous levels of TRMT5 at Human, Mouse |
| Gene Name | TRMT5 KIAA1393 TRM5 |
| Protein Name | tRNA (guanine(37)-N1)-methyltransferase (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog) |
| Other Name | |
| Species | Human |
| Gene ID | 57570 |
| Uniprot | Q32P41, |
| Species.1 | Mouse |
| Gene ID.1 | 76357 |
| Uniprot.1 | Q9D0C4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion matrix . Nucleus . Cytoplasm . Predominantly in the mitochondria and in the nucleus. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in mitochondrial tRNA methylation . Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. |
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