Name: Tyro3 Monoclonal Antibody
SKU: WM0458
Price: 268 USD
Availability: InStock

Tyro3 Monoclonal Antibody

Ucallm_WM0458-50

Price range: $268.00 through $328.00

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50μl

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SKU: WM0458-50

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Product details

Background:
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010],

Specifications

Target	Tyro3
Reactivity	Human
Applications	WB, IF, ELISA
MW(Calculated)	97kD
MW(Observed)
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification	Affinity purification
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	17C11
Immunogen	Purified recombinant fragment of Tyro3 expressed in E. Coli.
Sequence
Specificity	Tyro3 Monoclonal Antibody detects endogenous levels of Tyro3 protein.
Gene Name	TYRO3
Protein Name	Tyrosine-protein kinase receptor TYRO3
Other Name	TYRO3; / BYK; / DTK; / RSE; / SKY; / Tyrosine-protein kinase receptor TYRO3; / Tyrosine-protein kinase DTK; / Tyrosine-protein kinase RSE; / Tyrosine-protein kinase SKY; / Tyrosine-protein kinase byk
Species	Human
Gene ID-1	7301
Uniprot	Q06418,
Species.1	Mouse
Gene ID-2
Uniprot.1	P55144
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010],
Cellular Localization	Cell membrane; Single-pass type I membrane protein.
Tissue Expression	Abundant in the brain and lower levels in other tissues.
Signaling_pathway
Research Areas
Function	Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,Function:May be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Monomer and homodimer. Interacts with GAS6.,tissue specificity:Abundant in the brain and lower levels in other tissues.,
RRID