Specifications
| Size | 50μL/100μL |
| Target | AF-10 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 113kD |
| MW(Observed) | 130kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1742R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | MLLT10 |
| Protein Name | Protein AF-10 |
| Other Name | MLLT10; / AF10; / Protein AF-10; / ALL1-fused gene from chromosome 10 protein |
| Species | Human |
| Gene ID | 8028 |
| Uniprot | P55197, |
| Species.1 | Mouse |
| Gene ID.1 | 17354 |
| Uniprot.1 | O54826 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed abundantly in testis. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10; 11)(p12; q23) with MLL/HRX. The result is a rogue activator protein.,Disease:A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10; 11)(p13; q14) with PICALM.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PHD-type zinc fingers.,tissue specificity:Expressed abundantly in testis., |
