Name: U-Blot® ARC Rabbit mAb
SKU: WR5076
Price: 268 USD
Availability: InStock

U-Blot® ARC Rabbit mAb

Ucallm_WR5076-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WR5076-100

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Product details

Background:function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,similarity:Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,

Specifications

Size	50μL/100μL
Target	ARC
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	45kD
MW(Observed)	55kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1:1000; WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1315R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	ARC KIAA0278
Protein Name	Activity-regulated cytoskeleton-associated protein (ARC/ARG3.1) (Activity-regulated gene 3.1 protein homolog) (Arg3.1)
Other Name
Species	Human
Gene ID	23237
Uniprot	Q7LC44,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q9WV31,
Species.2	Rat
Gene ID.2
Uniprot.2	Q63053
Cellular Localization	Extracellular vesicle membrane; Lipid-anchor . Cell junction, synapse, postsynaptic cell membrane; Lipid-anchor . Cell junction, synapse . Cell junction, synapse, postsynaptic density . Early endosome membrane . Cell projection, dendrite . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cell projection, dendritic spine . Cytoplasmic vesicle, secretory vesicle, acrosome . Forms virion-like extracellular vesicles that are released from neurons. Enriched in postsynaptic density of dendritic spines. Targeted to inactive synapses following interaction with CAMK2B in the kinase inactive state. Accumulation at weaker synapses may be required to prevent their undesired enhancement. Associated with the cell cortex of neuronal soma and dendrites (By similarity). Associated with the sperm tail (By similarity). .
Tissue Expression	Brain,Forebrain,Uterus,
Signaling_pathway
Research Areas	>>Amphetamine addiction
Function	Function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,similarity:Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,

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U-Blot® ARC Rabbit mAb

Product details

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U-Blot® ARC Rabbit mAb

Product details

Specifications

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