U-Blot® ATF-5 Rabbit mAb
Ucallm_WR5844-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ATF5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 31kD |
| MW(Observed) | 35kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1813R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | ATF5 |
| Protein Name | Cyclic AMP-dependent transcription factor ATF-5 |
| Other Name | ATF5; / ATFX; / Cyclic AMP-dependent transcription factor ATF-5; / cAMP-dependent transcription factor ATF-5; / Activating transcription factor 5; / Transcription factor ATFx |
| Species | Human |
| Gene ID | 22809 |
| Uniprot | Q9Y2D1, |
| Species.1 | Mouse |
| Gene ID.1 | 107503 |
| Uniprot.1 | O70191, |
| Species.2 | Rat |
| Gene ID.2 | 282840 |
| Uniprot.2 | Q6P788 |
| Cellular Localization | Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. . |
| Tissue Expression | Widely expressed with higher expression levels in liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2., |
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