Product details
Background：
U-Blot® Caveolin-3 Rabbit mAb
Ucallm_WR5932-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CAV3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 17kD |
| MW(Observed) | 20kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1917R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | CAV3 |
| Protein Name | Caveolin-3 (M-caveolin) |
| Other Name | |
| Species | Human |
| Gene ID | 859 |
| Uniprot | P56539, |
| Species.1 | Mouse |
| Gene ID.1 | 12391 |
| Uniprot.1 | P51637, |
| Species.2 | Rat |
| Gene ID.2 | 29161 |
| Uniprot.2 | P51638 |
| Cellular Localization | Golgi apparatus membrane; Peripheral membrane protein . Cell membrane; Peripheral membrane protein . Membrane, caveola; Peripheral membrane protein . Cell membrane, sarcolemma . Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). . |
| Tissue Expression | Expressed predominantly in muscle. |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion;Human Diseases >> Neurodegenerative disease >> Prion disease |
| Research Areas | |
| Function | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae . |
Please login to post questions
Related products
