U-Blot® Citrulline-NPM1 (Arg196) Rabbit pAb
Ucallm_WT9047-100
Price range: $288.00 through $368.00
Product details
Background：
Nucleophosmin(NPM1) isaputativeribosomeassemblyfactorwithahighaffinityforpeptidescontainingnuclear localizationsignals(NLSs). Thetransportofproteinsacrossthenuclearenvelopeisaselective,multistepprocessinvolvingseveralcytoplasmicfactors.Proteinsmustbe recognizedasimportsubstrates,dockat thenuclearporecomplexandtranslocateacrossthenuclearenvelopeinanATP-dependent fashion.Severalcytosolicandnuclearproteinsthatarecentral tothisprocesshavebeenidentified.NPM1isinvolvedinribosomalassembly andrRNAtransport. It ishighlyphosphorylatedbyCdc2kinaseduringmitosis
Specifications
| Target | Citrullinated-Nucleophosmin (Arg196) |
| Reactivity | Human |
| Application | WB |
| MW(Calculated) | 33 kDa |
| MW(Observed) | 38 kDa |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Citrullination |
| Modified site | Arg196 |
| Recommended dilution ratio | WB: 1:1000-1:2000 |
| Composition | PBS, Glycerol, BSA |
| Source | |
| Purification process | Protein A and antigen purified |
| Purity | |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | polypeptide |
| Sequence | |
| Specificity | Specific for Nucleophosmin only when citrullinated at Arg196 |
| Gene name | NPM1 |
| Protein Name | Nucleophosmin |
| Alternative name | Numatrin, NMP, NMP1 |
| Organism-1 | Human |
| Gene ID-1 | 4869 |
| SwissProt-1 | P06748 |
| Organism-2 | |
| Gene ID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus,nucleoplasm |
Please login to post questions
Related products
