U-Blot® Histone H2A (Phospho Ser129) Rabbit pAb
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Price range: $380.00 through $950.00
Product details
Background:Histone H2A is one of the core components of the nucleosome, the basic building block of chromatin. Unlike mammals that have a distinct DNA damage- responsive histone H2A variant, H2AX, budding yeast histone H2A contains an SQ motif in the C-terminus that is phosphorylated by the Mec1 and Tel1 kinases in response to DNA double strand breaks. As with mammalian H2AX phosphorylation, phosphorylation of yeast histone H2A at serine 129 is required for the efficient repair of DNA double-strand breaks.
Specifications
| Target | Histone H2A |
| Reactivity | Budding Yeast, Wide Range Predicted |
| Application | ChIP,WB,DB |
| MW(Calculated) | |
| MW(Observed) | 14 kDa |
| Host Species | Rabbit |
| Isotype | Serum |
| Conjugate | Unconjugated |
| Modification | Phospho |
| Modification site | Ser129 |
| Recommended dilution ratio | WB 1:500 - 1:2,000 dilution |
| Formulation | Rabbit serum containing 30% glycerol and 0.035% sodium azide. |
| Source | |
| Purification | |
| Purity | |
| Storage | -20°C/2 year. Avoid freeze/thaw cycles. |
| Concentration | |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | This Histone H2A phospho Ser129 antibody was raised against a peptide including phospho-serine 129 of budding yeast Histone H2A. |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein name | |
| Alternative name | H2AS129ph |
| Organism-1 | |
| Gene ID‑1 | |
| SwissProt-1 | |
| Organism-2 | |
| Gene ID‑2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID‑3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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