U-Blot® Histone H3 (Dimethyl Lys56) Rabbit pAb
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Price range: $380.00 through $950.00
Product details
Background:Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Chromatin is subject to a variety of chemical modifications, including post- translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression.
Specifications
| Target | Histone H3 |
| Reactivity | Human, Wide Range Predicted |
| Application | ChIP,ChIP-Seq,WB,IF,DB,ICC |
| MW(Calculated) | |
| MW(Observed) | 17 kDa |
| Host Species | Rabbit |
| Isotype | Serum |
| Conjugate | Unconjugated |
| Modification | Di Methyl |
| Modification site | Lys56 |
| Recommended dilution ratio | DB 1:20,000 dilution; WB 1:5,000 - 1:20,000 dilution |
| Formulation | Rabbit serum containing 30% glycerol and 0.035% sodium azide. |
| Source | |
| Purification | |
| Purity | |
| Storage | -20°C/2 year. Avoid freeze/thaw cycles. |
| Concentration | |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | This Histone H3 dimethyl Lys56 antibody was raised against a peptide including dimethyl-lysine 56 of human histone H3. |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein name | |
| Alternative name | H3K56me2 |
| Organism-1 | |
| Gene ID‑1 | |
| SwissProt-1 | |
| Organism-2 | |
| Gene ID‑2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID‑3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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