U-Blot® Histone H4 (Propionyl Lys5) Rabbit mAb
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Price range: $400.00 through $1,000.00
Product details
Background:Histones are subject to a variety of enzyme catalyzed modifications, including acetylation, methylation, phosphorylation, ubiquitylation, etc. Lysine propionylation (Kprop) is structurally similar to lysine acetylation, is a newly identified reversible modification controlling protein activity. Lysine propionylation is abundant in both prokaryotes and eukaryotes and has been found in wide ranges of proteins including histones and non-histone substrates, such as p53. Similar to acetylation of histone H4 at Lys5, propionylation of histone H4 at Lys5 may play a vital role in the epigenetic modulation, including chromatin remodeling and transcriptional regulation.
Specifications
| Target | Histone H4 |
| Reactivity | Human,Mouse,Rat |
| Application | ICC, IHC-P, WB, ChIP |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Propionyl |
| Modification site | Lys5 |
| Recommended dilution ratio | WB 1:1000; IHC 1:2000; ICC 1:500; ChIP 1:20‑1:50 |
| Formulation | PBS, 40% Glycerol, 0.05% BSA, 0.03% ProClin 300 |
| Source | |
| Purification | Protein A |
| Purity | |
| Storage | 12 months from date of receipt / reconstitution, -20 ℃ as supplied |
| Concentration | 0.5 mg/ml |
| Clonality | Recombinant Monoclonal |
| Clone Number | WR-260 |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein name | |
| Alternative name | H4K5pr |
| Organism-1 | Human |
| Gene ID‑1 | 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370 |
| SwissProt-1 | P62805 |
| Organism-2 | Mouse |
| Gene ID‑2 | 100041230 |
| SwissProt-2 | P62806 |
| Organism-3 | Rat |
| Gene ID‑3 | 100360950 |
| SwissProt-3 | P62804 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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