$999.00
The affinity purified rabbit polyclonal anti-acetylated lysine antibody was developed using a unique technique that utilizes acetylated KLH as the immunogen and acetylated lysine-specific antibodies. It was specifically purified with immobilized acetylated lysine on agarose. The purified antibody is conjugated to fluorescein isothiocyanate.
| Target | Acetyllysine |
| Reactivity | Species Independent |
| Application | For direct immunofluorescence experiments |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | FITC/Ab ratio - 10:1, followed by G25 filtration |
| Modification | Lysine acetylation |
| Modified site | Lys（K） |
| Recommended dilution ratio | |
| Composition | 250 ug/mL antibody in PBS, pH 7, with 50% glycerol |
| Purification process | The antibody was purified on acetyl-lysine agarose |
| Purity | |
| Storage | Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. |
| Stability | Expiration date is six months from date of shipping if properly stored. |
| Clonal | Polyclonal |
| Clone Number | |
| Immunogen | Acetylated KLH conjugates |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein Name | |
| Alternative name | Kac |
| Organism-1 | |
| GeneID-1 | |
| SwissProt-1 | |
| Organism-2 | |
| GeneID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| GeneID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Background | Acetyllysine (abbreviated as Kac) is a classic and widespread post-translational modification of lysine acetylation. This modification covalently adds an acetyl group to the side-chain amino group of lysine residues, altering the charge and structure of proteins to regulate their functions. Lysine acetylation is an important epigenetic marker on histones, involved in chromatin remodeling and gene transcription regulation. It also widely exists in non-histone proteins such as metabolic enzymes, signaling proteins, and transcription factors, playing essential roles in cellular metabolism, signal transduction, cell cycle progression, and DNA repair. Dysregulation of lysine acetylation is closely associated with the development of cancer, metabolic diseases, neurodegenerative diseases, and other disorders. |
| Cellular Localization |
