Name: U-Blot® Research Grade Ozuriftamab
SKU: WA3319
Price: 9999 USD
Availability: InStock

U-Blot® Research Grade Ozuriftamab

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$9,999.00

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SKU: WA3319-50

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Product details

Background：Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC.
• A proteogenomic portrait of lung squamous cell carcinoma., PMID:34358469
• WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth., PMID:36622276
• ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma., PMID:38975886
• Robinow syndrome., PMID:12011143
• Ror2 as a therapeutic target in cancer., PMID:25614331
• Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis., PMID:31174180
• Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis., PMID:32951408
• The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis., PMID:23233346
• Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer., PMID:36463543
• Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2)., PMID:30826310

Specifications

Target	ROR2
Reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host Species	Humanized
Isotype	IgG1-kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition	0.01M PBS, pH 7.4.
Purification Process	Protein A/G purified from cell culture supernatant.
Purity	>95% purity as determined by SDS-PAGE.
Storage Condition	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
Clonality	Monoclonal
Clone Number
Immunogen	Mammalian Cells
Gene Name
Protein Name
Alias	ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
Species
Gene ID-1	Q01974
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Description	Background：Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC.<br>• A proteogenomic portrait of lung squamous cell carcinoma., PMID:34358469<br />• WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth., PMID:36622276<br />• ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma., PMID:38975886<br />• Robinow syndrome., PMID:12011143<br />• Ror2 as a therapeutic target in cancer., PMID:25614331<br />• Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis., PMID:31174180<br />• Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis., PMID:32951408<br />• The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis., PMID:23233346<br />• Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer., PMID:36463543<br />• Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2)., PMID:30826310<br />
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function