Background:Simridarlimab is a humanized IG antibody targeting CD274/CD47.
Specifications
Target
CD1
Reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host Species
Humanized
Isotype
(G1_L-kappa)_VH-VH-h-CH2-CH3
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition
0.01M PBS, pH 7.4.
Purification Process
Protein A/G purified from cell culture supernatant.
Purity
>95% purity as determined by SDS-PAGE.
Storage Condition
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
Clonality
Monoclonal
Clone Number
Immunogen
Mammalian Cells
Gene Name
Protein Name
Alias
B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6
Species
Gene ID-1
Q9NZQ7 & Q08722
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Description
Background:Simridarlimab is a humanized IG antibody targeting CD274/CD47.<br>