Product details
Background：Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary.
• CD52 antigen–a review., PMID:11257744
• Anti-CD52 Therapy for Multiple Sclerosis: An Update in the COVID Era., PMID:34268256
• CD52 mRNA expression predicts prognosis and response to immune checkpoint blockade in melanoma., PMID:37975535
• ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Agents targeting lymphoid cells surface antigens [I]: CD19, CD20 and CD52)., PMID:29447988
• Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors., PMID:38242120
• The immunological function of CD52 and its targeting in organ transplantation., PMID:28283679
• CD52 (CAMPATH1)., PMID:11860230
• Preoperative CD52 Level Predicts Graft Survival following Kidney Transplantation., PMID:39281063
• CD52 and OXPHOS-potential targets in ibrutinib-treated mantle cell lymphoma., PMID:36587029
• CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation., PMID:33731828
