Specifications
| Size | 50μL/100μL |
| Target | TBX3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, IP, ELISA |
| MW(Calculated) | 79kD |
| MW(Observed) | 79kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1776R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | TBX3 |
| Protein Name | T-box transcription factor TBX3 |
| Other Name | TBX3; / T-box transcription factor TBX3; / T-box protein 3 |
| Species | Human |
| Gene ID | 6926 |
| Uniprot | O15119, |
| Species.1 | Mouse |
| Gene ID.1 | 21386 |
| Uniprot.1 | P70324, |
| Species.2 | Rat |
| Gene ID.2 | 353305 |
| Uniprot.2 | Q7TST9 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells |
| Research Areas | >>Signaling pathways regulating pluripotency of stem cells |
| Function | Disease:Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.,Function:Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Widely expressed., |
