Price range: $268.00 through $328.00
Background：
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers , this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq , Jul 2008] ,
| Size | 50μL/100μL |
| Target | ZHX2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | 92kD |
| MW(Observed) | 110kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM2001R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | ZHX2 |
| Protein Name | Zinc fingers and homeoboxes protein 2 |
| Other Name | ZHX2; / AFR1; / KIAA0854; / RAF; / Zinc fingers and homeoboxes protein 2; / Alpha-fetoprotein regulator 1; / AFP regulator 1; / Regulator of AFP; / Zinc finger and homeodomain protein 2 |
| Species | Human |
| Gene ID | 22882 |
| Uniprot | Q9Y6X8, |
| Species.1 | Mouse |
| Gene ID.1 | 387609 |
| Uniprot.1 | Q8C0C0 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Colocalizes with EFNB1 intracellular domain in the nucleus. . |
| Tissue Expression | Ubiquitously expressed. Expressed in podocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Acts as a transcriptional repressor.,similarity:Belongs to the ZHX family.,similarity:Contains 2 C2H2-type zinc fingers.,similarity:Contains 4 homeobox DNA-binding domains.,subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.,tissue specificity:Ubiquitously expressed., |
