Product details
TCEP-HCl, with a molecular formula of C9H15O6P·HCl and a molecular weight of 286.65 (CAS: 51805-45-9), is a highly efficient reducing agent and deprotecting agent for thiolated DNA. It serves as a substitute for DTT in many applications.
Product Features
- Stable and Water-Soluble: Odorless and highly soluble, TCEP is stable in air and aqueous solutions, unaffected by temperature and concentration.
- Efficient and Mild: Provides strong reducing capability with low toxicity and ease of operation. Reaction effects last for 2–3 weeks, making it suitable for extended applications.
- Thiol-Free:TCEP selectively reduces disulfide bonds without containing thiol groups, often eliminating the need for removal after reaction.
Parameter table
| CAS No.: | 51805-45-9 |
| Formula: | C9H16CIO6P |
| Molecular: | 286.647 |
| Density | 1.041 g/mL at 25 C |
| Melting Point | 177°C |
| Water Solubility | Soluble in water and methanol. |
| Solubility | H20: 50 mg/mL |
| Appearance | White crystalline powder |
| Specific Gravity | white |
| PH | 7.0 (aqueous solution; pH adjusted with oxidation) |
| Storage Condition | 2-8°C, protected from light and moisture |
| Refractive Index | n20/D 1.367 |
Structural formula


