Product details
Background:
UCHL5 rabbit pAb
Ucallm_WP6635-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | UCHL5 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 36kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human UCHL5 |
| Specificity | This antibody detects endogenous levels of UCHL5 at Human, Mouse |
| Gene Name | UCHL5 UCH37 AD-019 CGI-70 |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5) |
| Other Name | |
| Species | Human |
| Gene ID | 51377 |
| Uniprot | Q9Y5K5, |
| Species.1 | Mouse |
| Gene ID.1 | 56207 |
| Uniprot.1 | Q9WUP7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus. |
| Tissue Expression | |
| Signaling_pathway | Genetic Information Processing >> Chromosome >> ATP-dependent chromatin remodeling |
| Research Areas | |
| Function | Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. |
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