Product details
Background:
This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012],
ZER1 rabbit pAb
Ucallm_WP3725-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ZER1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZER1 AA range: 388-438 |
| Specificity | This antibody detects endogenous levels of ZER1 at Human/Mouse |
| Gene Name | ZER1 C9orf60 ZYG ZYG11BL |
| Protein Name | ZER1 |
| Other Name | Protein zer-1 homolog; / Hzyg; / Zyg-11 homolog B-like protein |
| Species | Human |
| Gene ID | 10444 |
| Uniprot | Q7Z7L7, |
| Species.1 | Mouse |
| Gene ID.1 | 227693 |
| Uniprot.1 | Q80ZJ6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cul2-RING ubiquitin ligase complex, |
| Tissue Expression | Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas., |
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