Product details
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ZFYVE16 rabbit pAb
Ucallm_WP6496-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ZFYVE16 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 169kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZFYVE16 |
| Specificity | This antibody detects endogenous levels of ZFYVE16 at Human, Mouse |
| Gene Name | ZFYVE16 KIAA0305 |
| Protein Name | Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein) |
| Other Name | |
| Species | Human |
| Gene ID | 9765 |
| Uniprot | Q7Z3T8, |
| Species.1 | Mouse |
| Gene ID.1 | 218441 |
| Uniprot.1 | Q80U44 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Early endosome membrane; Peripheral membrane protein . Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P). |
| Tissue Expression | Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes. |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway |
| Research Areas | |
| Function | May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. |
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