Name: Aurora A Mouse mAb [2B3]
SKU: WM1118
Price: 268 USD
Availability: InStock

Aurora A Mouse mAb [2B3]

Ucallm_WM1118-50

Price range: $268.00 through $328.00

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SKU: WM1118-50

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Product details

Background:
Aurora A(AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Specifications

Target	Aurora A
Reactivity	Human, Mouse, Rat
Applications	IHC, WB
MW(Calculated)
MW(Observed)	46kD
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	IHC1:50-200; WB 1:1000-2000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Monoclonal
Clone Number	2B3
Immunogen	Synthesized peptide derived from human Aurora A
Sequence
Specificity	This antibody detects endogenous levels of Aurora A at Human, Mouse,Rat
Gene Name	AURKA
Protein Name	Aurora A
Other Name
Species	Human
Gene ID-1	6790
Uniprot	O14965
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	Aurora A(AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID