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Home/Reagents/Antibody/Primary antibody/Monoclonal Antibody/Mouse mAb/Casein Kinase Iα Monoclonal Antibody
SKU: WM0073 Categories: ,

Casein Kinase Iα Monoclonal Antibody

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Price range: $499.00 through $699.00

SKU: WM0073-50
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Product details

Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on ‘Ser-45’., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily., similarity:Contains 1 protein kinase domain., subunit:Monomer. Interacts with the Axin complex.,

Specifications

Specification50μL;100μL
TargetCasein Kinase Iα
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)39kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessAffinity purification
Puity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenPurified recombinant fragment of Casein Kinase Iα expressed in E. Coli.
Sequence
SpecificityCasein Kinase Iα Monoclonal Antibody detects endogenous levels of Casein Kinase Iα protein.
Gene NameCSNK1A1
Protein NameCasein kinase I isoform alpha
AliasCSNK1A1;Casein kinase I isoform alpha;CKI-alpha;CK1
Organism-1Human
Gene ID-11452
SwissProt-1P48729
Organism-2Mouse
Gene ID-2
SwissProt-2Q8BK63
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome, centromere, kinetochore . Nucleus speckle . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, spindle . Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688). .
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