SKU: WM0349 Categories: ,

OCT1 Monoclonal Antibody

Price range: $268.00 through $328.00

SKU: WM0349-50
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Product details

Background:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008],

Specifications

Specification50μL;100μL
TargetOCT1
ReactivityHuman
ApplicationsWB, Flow Cyt, ELISA
MW(Calculated)61kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessAffinity purification
Puity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenPurified recombinant fragment of human OCT1 expressed in E. Coli.
Sequence
SpecificityOCT1 Monoclonal Antibody detects endogenous levels of 41183 protein.
Gene NameSLC22A1
Protein NameSolute carrier family 22 member 1
AliasSLC22A1;OCT1;Solute carrier family 22 member 1;Organic cation transporter 1;hOCT1
Organism-1Human
Gene ID-16580
SwissProt-1O15245
Organism-2Mouse
Gene ID-2
SwissProt-2O08966
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationBasolateral cell membrane ; Multi-pass membrane protein .
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