SKU: WR4009 Categories: ,

U-Blot® VEGF Receptor 1 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4009-50
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Product details

Background:fms related tyrosine kinase 1(FLT1) Homo sapiens This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009],

Specifications

TargetFLT1
ReactivityHuman,Mouse,Rat,
ApplicationWB,IHC,IF,IP,ELISA
MW(Calculated)151kD
MW(Observed)180kD
Host SpeciesRabbit
ClonalMonoclonal
Clone numberPT0056R
Gene nameFLT1 FLT FRT VEGFR1
Protein nameVascular endothelial growth factor receptor 1 (VEGFR-1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
size100μl, 50μl
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Modification site
Recommended dilution ratioIHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification processProtein A
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Immunogen
Sequence
SpecificityEndogenous
Alternative nameVascular endothelial growth factor receptor 1;VEGFR-1;Fms-like tyrosine kinase 1;FLT-1;Tyrosine-protein kinase FRT;Tyrosine-protein kinase receptor FLT;FLT;Vascular permeability factor receptor;
Organism-1Human
Gene ID-12321
SwissProt-1P17948
Organism-2Mouse
Gene ID-214254
SwissProt-2P35969
Organism-3Rat
Gene ID-354251
SwissProt-3P53767
Organism-4
Gene ID-4
SwissProt-4
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