Price range: $268.00 through $328.00
Background:
The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
| Size | 50μL/100μL |
| Target | NFIC |
| Reactivity | Human |
| Applications | WB, ICC |
| MW(Calculated) | |
| MW(Observed) | 56kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:200; ICC 1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 12F2 |
| Immunogen | Purified recombinant human NFIC protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of NFIC and does not cross-react with related proteins. |
| Gene Name | NFIC |
| Protein Name | |
| Other Name | 1110019L22Rik; / 1500041O16Rik; / AA589446; / AI746521; / CAAT box transcription factor; / CCAAT binding transcription factor; / CCAAT box binding transcription factor; / CCAAT-box-binding transcription factor; / CNFI C; / CTF; / CTF5; / MGC137374; / MGC20153; / NF I; / NF I/C; / NF-I/C; / NF1 C; / NF1-C; / NF1C; / NFI; / NFI-C; / NFI/C; / NFIC; / NFIC_HUMAN; / Nuclear factor 1; / Nuclear factor 1 C type; / Nuclear factor 1 C-type; / Nuclear factor 1/C; / Nuclear factor I/C; / TGGCA binding protein; / TGGCA-binding protein; / Transcription factor NFIC. |
| Species | Human |
| Gene ID | 4782 |
| Uniprot | P08651 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Epithelium,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.,similarity:Belongs to the CTF/NF-I family.,similarity:Contains 1 CTF/NF-I DNA-binding domain.,subunit:Binds DNA as a homodimer., |
