Background:Semzuvolimab is a murine IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4). Murine CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection.
Specifications
Target
T-cell surface antigen T4/Leu-3
Reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host Species
Humanized
Isotype
IgG4-kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition
0.01M PBS, pH 7.4.
Purification Process
Protein A/G purified from cell culture supernatant.
Purity
>95% as determined by SDS-PAGE.
Storage Condition
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background:Semzuvolimab is a murine IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4). Murine CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection.<br>