SKU: WR4012 Categories: ,

U-Blot® CDC37 (Phospho Ser13) Rabbit mAb

Price range: $288.00 through $368.00

SKU: WR4012-50
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Product details

Background:The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008],

Specifications

TargetCdc37
ReactivityHuman,Mouse,Rat,
ApplicationWB,IHC,IF,IP,ELISA
MW(Calculated)44kD
MW(Observed)44kD
Host SpeciesRabbit
ClonalMonoclonal
Clone numberPT0060R
Gene nameCDC37
Protein nameHsp90 co-chaperone Cdc37
size100μl, 50μl
IsotypeIgG,Kappa
Conjugate/ModificationPhospho
Modification siteSer13
Recommended dilution ratioIHC 1:400-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification processProtein A
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Immunogen
Sequence
SpecificityThis antibody detects endogenous levels of CDC37 only when phosphorylated at Ser13.
Alternative nameCDC37;CDC37A;Hsp90 co-chaperone Cdc37;Hsp90 chaperone protein kinase-targeting subunit;p50Cdc37
Organism-1Human
Gene ID-111140
SwissProt-1Q16543
Organism-2Mouse
Gene ID-212539
SwissProt-2Q61081
Organism-3Rat
Gene ID-3114562
SwissProt-3Q63692
Organism-4
Gene ID-4
SwissProt-4
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