SKU: WM9712 Categories: ,

U-Blot® Trem1 mIgG2a Antibody

$999.00

SKU: WM9712-5
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Product details

Background:Trem1 (Triggering Receptor Expressed on Myeloid cells 1) is a key amplifier of inflammatory responses and is overactivated in conditions such as sepsis, pneumonia, inflammatory bowel disease, and acute pancreatitis, contributing to cytokine storms and tissue damage. U-Blot? Trem1 antibodies or inhibitors can block this signaling pathway, thereby alleviating hyperinflammation and restoring immune homeostasis. Recent studies also suggest that targeting Trem1 may improve the tumor immune microenvironment and enhance U-Blot? tumor immunity. Thus, U-Blot? Trem1 not only offers a novel therapeutic strategy for inflammatory diseases but also opens new avenues for precision immunomodulation and biologic drug development. Its potential for clinical translation warrants further investigation.

Specifications

TargetTrem1
ReactivityMouse
ApplicationsFlow Cytometry
MW(Calculated)
MW(Observed)
Host SpeciesMouse
IsotypeIgG2a,
Conjugate/ModificationUnconjugated
Modification
Recommended Dilution RatioWesternblotting: 1:1000-1:5000; FC-Quality tested
Formulation BufferPhosphate-buffered solution, pH 7.2-7.4
Source
Purification
Purity> 95% as determined by SDS-PAGE
StorageStore at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term.Avoid repeated freeze-thaw.
Concentration
ClonalityMonoclonal
Clone Number
Immunogen
Sequence
Specificity
Gene Name
Protein Name
Other NameTrem-1, CD354
Species
Gene ID
Uniprot
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Organism-4
GeneID-4
SwissProt-4
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID
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