U-Blot® c-Kit(CD117) hIgG4 Reference Antibody (Bribio)

$999.00

SKU: WE2686-50
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Product details

Background:CD117 (also known as c-KIT or SCF receptor) is a gene that encodes the Stem Cell Factor Receptor (SCFR) and belongs to the type I tyrosine kinase receptor family. Briquilimab works by binding to CD117, blocking the function of the Stem Cell Factor receptor and thereby affecting the behavior of cells dependent on the CD117 signaling pathway. As an innovative monoclonal antibody targeting CD117, Briquilimab has shown significant potential in hematopoietic stem cell transplantation, immune regulation, and the treatment of related diseases, making it a promising low-toxicity and highly effective novel therapy.

Specifications

Targetc-Kit
Reactivity
ApplicationsFlow Cytometry
MW(Calculated)
MW(Observed)
Host SpeciesHuman
IsotypeIgG1,
Conjugate/ModificationUnconjugated
Modification
Recommended Dilution Ratio
Formulation Bufferphosphate-buffered solution, pH 7.4.
Source
Purification
Purity> 95% as determined by SDS-PAGE
StorageStore at 2-8℃ short term (1-2 weeks).Store at ≤ -99℃ long term.Avoid repeated freeze-thaw.
Concentration
ClonalityMonoclonal
Clone NumberBriquilimab
Immunogen
Sequence
Specificity
Gene Name
Protein Name
Other NameC-Kit, CD117, MASTC, PBT, SCFR
Species
Gene ID
Uniprot
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Organism-4
GeneID-4
SwissProt-4
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID
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