Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | TRI35 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 54kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 320-400 |
| Specificity | TRI35 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TRIM35 HLS5 KIAA1098 |
| Protein Name | Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5) |
| Other Name | |
| Species | Human |
| Gene ID | 23087 |
| Uniprot | Q9UPQ4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C006, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5RKG6 |
| Cellular Localization | Cytoplasm . Nucleus . Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity). . |
| Tissue Expression | Brain,Liver,Lung, |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.,Function:May play a role as a tumor suppressor. Implicated in the cell death mechanism.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies., |
