Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | K1H1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | K1H1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | KRT31 HHA1 HKA1 KRTHA1 |
| Protein Name | Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31) |
| Other Name | |
| Species | Human |
| Gene ID | 3881 |
| Uniprot | Q15323, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q61765 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | extracellular space,intermediate filament,extracellular exosome, |
| Tissue Expression | Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Estrogen signaling pathway |
| Research Areas | >>Estrogen signaling pathway; / >>Staphylococcus aureus infection |
| Function | miscellaneous:There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).,similarity:Belongs to the intermediate filament family.,tissue specificity:Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla., |
