Price range: $268.00 through $328.00
Background:
function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome., induction:By MYC., similarity:Belongs to the WD repeat BOP1/ERB1 family., similarity:Contains 7 WD repeats., subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,
| Size | 50μL/100μL |
| Target | BOP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 82kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 110-190 |
| Specificity | BOP1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | BOP1 KIAA0124 |
| Protein Name | Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein) |
| Other Name | |
| Species | Human |
| Gene ID | 23246 |
| Uniprot | Q14137, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P97452, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q562C2 |
| Cellular Localization | Nucleus, nucleolus . Nucleus, nucleoplasm . |
| Tissue Expression | Bone marrow,Brain,Epithelium,Eye,Liver,Lymph,Muscle,Pancreas, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome., |
