SKU: WP1938 Categories: ,

VAX1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1938-100
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Product details

Background:

This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetVAX1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)36kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityVAX1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameVAX1
Protein NameVentral anterior homeobox 1
Other Name
SpeciesHuman
Gene ID11023
UniprotQ5SQQ9,
Species.1Mouse
Gene ID.1
Uniprot.1Q2NKI2,
Species.2Rat
Gene ID.2
Uniprot.2Q9JM00
Cellular LocalizationNucleus .
Tissue ExpressionBrain,
Signaling_pathway
Research Areas
FunctionFunction:Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.,similarity:Belongs to the EMX homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
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