Price range: $268.00 through $328.00
Background:
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012],
| Size | 50μL/100μL |
| Target | FN3K |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 33kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 130-210 |
| Specificity | FN3K Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | FN3K |
| Protein Name | Fructosamine-3-kinase (EC 2.7.1.-) |
| Other Name | |
| Species | Human |
| Gene ID | 64122 |
| Uniprot | Q9H479, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9ER35 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytosol, |
| Tissue Expression | Widely expressed (PubMed:11522682). Expressed in erythrocytes (PubMed:11016445). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme.,similarity:Belongs to the fructosamine kinase family.,subunit:Monomer.,tissue specificity:Expressed in erythrocytes., |
