SKU: WP2459 Categories: ,

DNER Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2459-100
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Product details

Background:

function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis., similarity:Contains 1 follistatin-like domain., similarity:Contains 10 EGF-like domains., subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region., subunit:Interacts with AP1G1. Interacts with NOTCH1., tissue specificity:Expressed in brain, spinal cord and adrenal gland.,

Specifications

Size50μL/100μL
TargetDNER
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)81kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityDNER Polyclonal Antibody detects endogenous levels of protein.
Gene NameDNER BET UNQ262/PRO299
Protein NameDelta and Notch-like epidermal growth factor-related receptor
Other Name
SpeciesHuman
Gene ID92737
UniprotQ8NFT8,
Species.1Mouse
Gene ID.1
Uniprot.1Q8JZM4
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). .
Tissue ExpressionExpressed in brain, spinal cord and adrenal gland.
Signaling_pathway
Research Areas
FunctionFunction:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.,similarity:Contains 1 follistatin-like domain.,similarity:Contains 10 EGF-like domains.,subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.,subunit:Interacts with AP1G1. Interacts with NOTCH1.,tissue specificity:Expressed in brain, spinal cord and adrenal gland.,
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