SKU: WR4004 Categories: ,

U-Blot® Cleaved PARP1 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4004-50
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Product details

Background:This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Specifications

TargetPARP1
ReactivityHuman,Mouse,Rat,
ApplicationWB,IHC,IF,ELISA
MW(Calculated)25kD
MW(Observed)25kD
Host SpeciesRabbit
ClonalMonoclonal
Clone numberPT0046R
Gene namePARP1
Protein namePoly [ADP-ribose] polymerase 1
size100μl, 50μl
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Modification site
Recommended dilution ratioIHC 1:200-1000;WB 1:500-5000;IF 1:200-1000;ELISA 1:5000-20000;
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification processProtein A
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Immunogen
Sequence
SpecificityThis antibody detects endogenous levels of Cleaved PARP1.
Alternative namePARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1
Organism-1Human
Gene ID-1142
SwissProt-1P09874
Organism-2Mouse
Gene ID-2
SwissProt-2P11103
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
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