SKU: WP2582 Categories: ,

ROBO4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2582-100
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Product details

Background:

function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins., similarity:Belongs to the immunoglobulin superfamily. ROBO family., similarity:Contains 2 fibronectin type-III domains., similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with SLIT2 and ENAH., tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.,

Specifications

Size50μL/100μL
TargetROBO4
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)110kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityROBO4 Polyclonal Antibody detects endogenous levels of protein.
Gene NameROBO4 UNQ421/PRO3674
Protein NameRoundabout homolog 4 (Magic roundabout)
Other Name
SpeciesHuman
Gene ID54538
UniprotQ8WZ75,
Species.1Mouse
Gene ID.1
Uniprot.1Q8C310,
Species.2Rat
Gene ID.2
Uniprot.2Q80W87
Cellular Localizationintegral component of membrane,extracellular exosome,
Tissue ExpressionSpecifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta (PubMed:30455415).
Signaling_pathway
Research Areas
FunctionFunction:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,similarity:Belongs to the immunoglobulin superfamily. ROBO family.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with SLIT2 and ENAH.,tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.,
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